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GSL Biotech clustal omega algorithm
Protein sequences for novel nanobodies that bind to the SARS-CoV-2 spike protein receptor binding domain. Single letter amino acid codes. <t>Clustal</t> <t>Omega</t> algorithm used for alignment. Blue highlights indicate sequence diversity with NIH-CoVnb-112, highlighted in gray, set as the reference sequence for comparison. For comparison, seven previously reported nanobody sequences have clearly distinct sequences: Ty1 , VHH72 , H11-D4 , MR3 , Sb#14 , Sb23 , and W25UACh and possess shorter CDR3 domains (represented in NIH-CoVnb-112 by amino acids 99–120).
Clustal Omega Algorithm, supplied by GSL Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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clustal omega algorithm - by Bioz Stars, 2026-06
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Protein sequences for novel nanobodies that bind to the SARS-CoV-2 spike protein receptor binding domain. Single letter amino acid codes. Clustal Omega algorithm used for alignment. Blue highlights indicate sequence diversity with NIH-CoVnb-112, highlighted in gray, set as the reference sequence for comparison. For comparison, seven previously reported nanobody sequences have clearly distinct sequences: Ty1 , VHH72 , H11-D4 , MR3 , Sb#14 , Sb23 , and W25UACh and possess shorter CDR3 domains (represented in NIH-CoVnb-112 by amino acids 99–120).

Journal: Scientific Reports

Article Title: High affinity nanobodies block SARS-CoV-2 spike receptor binding domain interaction with human angiotensin converting enzyme

doi: 10.1038/s41598-020-79036-0

Figure Lengend Snippet: Protein sequences for novel nanobodies that bind to the SARS-CoV-2 spike protein receptor binding domain. Single letter amino acid codes. Clustal Omega algorithm used for alignment. Blue highlights indicate sequence diversity with NIH-CoVnb-112, highlighted in gray, set as the reference sequence for comparison. For comparison, seven previously reported nanobody sequences have clearly distinct sequences: Ty1 , VHH72 , H11-D4 , MR3 , Sb#14 , Sb23 , and W25UACh and possess shorter CDR3 domains (represented in NIH-CoVnb-112 by amino acids 99–120).

Article Snippet: Sequences were trimmed to include only the VHH coding region and the protein coding sequences aligned using the Clustal Omega algorithm included in SnapGene software (GSL Biotech LLC).

Techniques: Binding Assay, Sequencing, Comparison